Brussels Rising: 13 Venture Capital Firms Driving Innovation in 2025
Brussels may be better known for politics and waffles — but in 2025, it's also an emerging hotspot for innovation. As Belgium's capital grows into a magnet for founders across Europe, venture capital firms in Brussels are stepping up to fund the next wave of breakthroughs in biotech, sustainable food, fintech, and deep tech.
Whether you're seeking your first check or looking to scale across the EU, this guide introduces top-tier VCs in Brussels and helpful tips to pitch smarter. I also include searches for investors in Brussels, helping you find the right fit.
Quick list of top venture capital firms in Brussels
- Astanor Ventures – Global leader in agrifood and sustainability tech
- Smartfin Capital – Growth-stage fintech and enterprise software investor
- Hummingbird Ventures – International VC with strong Brussels roots and global reach
- Theodorus – University-linked seed fund investing in health, engineering, and spin-offs
- Inventures Investment Partners – Impact investor supporting inclusive and green innovation
- ScaleFund – Early-growth VC investing in scalable tech ventures across Belgium
- Lab Box – Mobility-focused VC and venture builder
- Bioqube Ventures – Specialized biotech investor with strong EU research ties
- Belcube – Seed-stage fund backing Belgian founders in tech and consumer
- Innovation Fund – Corporate-backed fund focused on cleantech and industrial innovation
- Telos Impact – Belgian impact investment firm focused on social and sustainable ventures
- Solvay Ventures – Corporate VC of Solvay Group investing in advanced materials and circular economy
- PMV – Regional investment company supporting innovation and entrepreneurship in Flanders
How to find the right VC firm in Brussels
Choosing between VC firms in Brussels depends on your stage, sector, and regional goals. Here's how to narrow the list:
- Stage focus: Some firms like Belcube back seed-stage, others like Smartfin target growth
- Vertical match: Biotech? Fintech? Agrifood? Impact? Each firm leans into a niche
- Corporate vs. independent: PMV, Solvay Ventures, and Innovation Fund are institution-backed
- EU access: Brussels-based firms often help with EU grants and regulatory navigation
- Geographic goals: Some funds are Belgium-focused, others pan-European or global
Use the Papermark Investor Database to explore by geography, check size, and sector.
How to send your pitch deck to VC firms in Brussels
When reaching out to investors in Brussels, first impressions matter. A polished pitch sent the right way can make all the difference.
Here's how to do it right:
- Don't send static attachments — use Papermark to share a secure, trackable deck
- Customize your message — Brussels VCs are diverse; tailor by fund focus
- Be clear and concise — traction, team, roadmap
- Mention EU relevance — grant access, regulation, or multilingual growth
- Follow up based on real analytics from link activity
Why use a pitch deck link instead of attachments?
- Get notified when an accelerator team opens your deck
- Track how long they were on each page of your deck
- Capture emails of those who viewed your deck
- Protect your IP using watermark, screenshot protection and other link permissions
- Securely send data room with multiple documents
Table
| Accelerator | Location | Investment Size | Program Length | Focus Areas | Success Rate |
|---|---|---|---|---|---|
| Astanor Ventures | Brussels, Belgium | €1 M – €10 M | Long‑term | Ag‑food, Planet‑positive | — |
| Smartfin Capital | Brussels, Belgium | €2 M – €15 M | Long‑term | B2B SaaS, Fin‑ & Deep‑tech | — |
| Hummingbird Ventures | Brussels, Belgium | $1 M – $5 M | Long‑term | Global software, Frontier | — |
| Theodorus | Brussels, Belgium | €0.5 M – €3 M | Long‑term | University spin‑outs, Life‑science | — |
| Inventures Investment Partners | Brussels, Belgium | €0.2 M – €2 M | Long‑term | Impact, Climate, Health | — |
| ScaleFund | Brussels, Belgium | €0.5 M – €3 M | Long‑term | Early‑stage Tech, Deep‑tech | — |
| Lab Box | Brussels, Belgium | €0.1 M – €1 M | Venture studio | Mobility, Transport, Digital | — |
| Bioqube Ventures | Brussels, Belgium | €1 M – €10 M | Long‑term | Life‑science, Therapeutics | — |
| Belcube | Brussels, Belgium | €0.1 M – €1 M | Long‑term | Angel‑VC, Digital | — |
| Innovation Fund | Brussels, Belgium | €0.25 M – €5 M | Long‑term | Industrial deep‑tech, Chemistry | — |
| Telos Impact | Brussels, Belgium | €0.25 M – €2 M | Long‑term | Impact, Sustainability | — |
| Solvay Ventures | Brussels, Belgium | €1 M – €5 M | Long‑term | Chem‑tech, Advanced materials | — |
| PMV | Brussels, Belgium | €0.5 M – €20 M | Long‑term | Growth capital, Flemish SMEs | — |
1. Astanor Ventures
Impact‑driven ag‑food investor backing regenerative, planet‑positive innovation.
- Focus: Ag‑food, Climate resilience, Circular bio‑economy
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €1 M – €10 M Series A–C
- Equity free: No
- Website: Astanor Ventures
2. Smartfin Capital
Pan‑European growth fund backing data‑driven B2B software.
- Focus: Fin‑tech, Cyber‑ & Deep‑tech, B2B SaaS
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €2 M – €15 M Series A–B
- Equity free: No
- Website: Smartfin Capital
3. Hummingbird Ventures
Global seed‑to‑growth VC supporting frontier‑tech disruptors.
- Focus: Software, Web 3, Frontier marketplaces
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: $1 M – $5 M seed/Series A
- Equity free: No
- Website: Hummingbird Ventures
4. Theodorus
Université libre de Bruxelles–linked fund turning research into ventures.
- Focus: Life‑science, Med‑tech, University spin‑outs
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.5 M – €3 M seed/Series A
- Equity free: No
- Website: Theodorus
5. Inventures Investment Partners
Impact VC financing solutions for climate, health, and inclusion.
- Focus: Impact tech, Climate solutions, Health‑tech
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.2 M – €2 M seed/Series A
- Equity free: No
- Website: Inventures Investment Partners
6. ScaleFund
Hands‑on early‑stage VC helping Belgian startups scale relentlessly.
- Focus: Digital, Deep‑tech, Cleantech
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.5 M – €3 M seed/Series A
- Equity free: No
- Website: ScaleFund
7. Lab Box
D'Ieteren‑backed venture studio building the future of mobility.
- Focus: Mobility, Transport, Automotive digitalisation
- Location: Brussels, Belgium
- Program length: Venture‑studio lifecycle (build → spin‑out)
- Investment: €0.1 M – €1 M per spin‑out
- Equity free: No
- Website: Lab Box
8. Bioqube Ventures
Trans‑Atlantic VC translating breakthrough science into tomorrow's therapies.
- Focus: Life‑science, Biotech platforms, Therapeutics
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €1 M – €10 M Series A–B
- Equity free: No
- Website: Bioqube Ventures
9. Belcube
Entrepreneur‑led angel‑VC fund mentoring Belgium's next tech champions.
- Focus: Early digital ventures, SaaS, Marketplaces
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.1 M – €1 M pre‑seed/seed
- Equity free: No
- Website: Belcube
10. Innovation Fund
Industrial innovation fund catalysing advanced materials & chemistry.
- Focus: Chemistry, Advanced materials, Cleantech
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.25 M – €5 M seed/Series A
- Equity free: No
- Website: Innovation Fund
11. Telos Impact
Impact manager & advisor investing for measurable social and environmental change.
- Focus: Climate, Education, Mental‑health
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.25 M – €2 M impact tickets
- Equity free: No
- Website: Telos Impact
12. Solvay Ventures
Corporate VC of Solvay Group driving chemistry‑powered breakthrough tech.
- Focus: Advanced materials, Battery tech, Circularity
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €1 M – €5 M Series A–B
- Equity free: No
- Website: Solvay Ventures
13. PMV (ParticipatieMaatschappij Vlaanderen)
Flemish public investment company funding scale‑ups and strategic sectors.
- Focus: Growth capital, Infrastructure, Innovation financing
- Location: Brussels, Belgium
- Program length: Long‑term partnership
- Investment: €0.5 M – €20 M debt & equity
- Equity free: No
- Website: PMV
Prepare for Demo Day: what Brussels investors expect
If you're pitching at a demo day or investor meeting, VCs in Brussels tend to value practicality and purpose. Expect sharp questions and a focus on execution.
To impress:
- Show market traction or validated tech
- Be clear about team roles and EU expansion plans
- Address impact or ESG if relevant
- Keep slides clean, visual, and structured
- Use Papermark to follow up with metrics
Didn't find the right investor?
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Final Thoughts
With a mix of global powerhouses and niche impact investors, Brussels' VC ecosystem is one of the most unique in Europe. Whether you're building biotech, clean energy, or fintech — the city's funds are ready to help you scale.
Use Papermark to share your pitch like a pro.